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Annex IV Entry 145 14/08/2020

Riboflavin

LACTOFLAVIN / RIBOFLAVIN

Riboflavin appears in Annex IV as a positive-list colorant entry for EU cosmetics.

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Permitted colorant— Annex IV, EU Regulation 1223/2009
Entry: 145

Record details

Warnings

Purity criteria as set out in Commission Directive 95/45/EC (E101)

Colour index or glossary

LACTOFLAVIN / RIBOFLAVIN

Chemical name

Riboflavin

Chemical / IUPAC name

1-deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)-D-ribitol

Color

Yellow

Regulatory information

Regulation

(EC) 2009/1223

Identified ingredients

Key data

CAS
—
EC
201-507-1 / 204-988-6
Annex
IV
Entry number
145

Inventory links for Riboflavin

Inventory Restriction reference
Ref 34829

LACTOFLAVIN

CAS: 83-88-5
EC: 201-507-1
Inventory Restriction reference
Ref 37498

RIBOFLAVIN

CAS: 83-88-5
EC: 201-507-1

Direct matches are limited for this record, so nearby entries from Annex IV are shown as well.

Annex IV 144
Nearby record in the same annex

ZINC OXIDE

CAS: 1314-13-2
EC: 215-222-5
Annex IV 146
Nearby record in the same annex

CARAMEL

EC: 232-435-9
Annex IV 142
Nearby record in the same annex

CI 77820

CAS: 7440-22-4
EC: 231-131-3
Annex IV 148
Nearby record in the same annex

BEETROOT RED

CAS: 7659-95-2; 89957-88-0; 89957-89-1
EC: 231-628-5; 289-609-2; 289-610-8
Annex IV 141
Nearby record in the same annex

CI 77745

CAS: 10124-54-6
EC: 233-341-0
Annex IV 149
Nearby record in the same annex

ANTHOCYANINS

CAS: 528-58-5 / 134-01-0 / 528-53-0 / 643-84-5 / 134-04-3
EC: 208-438-6 / 205-125-6 / 211-403-8 / 208-437-0 / - / 205-127-7
Annex IV 140
Nearby record in the same annex

CI 77742

CAS: 10101-66-3
EC: 233-257-4
Annex IV 139
Nearby record in the same annex

CI 77713

CAS: 546-93-0; 7757-69-9
EC: 208-915-9; 231-817-2

What Annex IV means for Riboflavin

Riboflavin is an approved colorant listed in Annex IV of EU Cosmetics Regulation 1223/2009. Only colorants on this positive list may be used to colour cosmetic products on the EU market.

Some colorants in Annex IV are restricted by product type — for example, prohibited from use around the eyes or in products applied to mucous membranes. Check the product type and conditions fields above before use.

This record is linked to 3 CosIng inventory ingredients for name and identifier cross-reference. The page also surfaces 12 related annex records with overlapping identifiers, annex logic or naming patterns.

Compliance checklist

  • Confirm colorant is used only in permitted product types listed above.
  • Record the Colour Index number and CAS identifier in the ingredient declaration.

Frequently asked questions

Yes. Riboflavin is included in Annex IV of EU Cosmetics Regulation 1223/2009 as a permitted colorant. Only colorants on this positive list may be used to colour cosmetic products in the EU. Check the product type conditions above for any use restrictions.

Use the INCI Checker tool on this site to paste your full ingredient list (INCI) and scan it against all Annex II–VI entries. The tool highlights any ingredients that match restricted, prohibited or allergen-flagged records. This is useful for rapid compliance screening of finished product formulas or raw material declarations.
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Source note for Annex IV record Riboflavin

This page summarizes one Annex IV record for Riboflavin from public European Commission cosmetic materials and adds linked inventory or identifier matches when available.

Use this record page to review Annex IV conditions for Riboflavin, but confirm any final regulatory decision against the current official annex wording and source files.

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