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Annex III Entry 377 04/04/2024

4-Hydroxyphenyl-alpha-D-glucopyranoside

Alpha-Arbutin

Key data

Annex
Entry number
377

Source and verification note

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Record details

INCI glossary name

Alpha-Arbutin

Chemical name

4-Hydroxyphenyl-alpha-D-glucopyranoside

Maximum concentration

(a) 2 % (b) 0,5 %

Other restrictions

Hydroquinone levels shall remain as low as possible in formulations containing alpha-Arbutin and shall not be higher than the unavoidable trace level.

From 1 February 2025 cosmetic products containing that substance and not complying with the conditions shall not be placed on the Union market. From 1 November 2025 cosmetic products containing that substance and not complying with the conditions shall not be made available on the Union market.

Regulatory information

Regulation

(EU) 2024/996

SCCS opinions

  • OPINION ON α-arbutin
  • Opinion on the safety of alpha- (CAS No. 84380-018, EC No. 617-561-8) and beta-arbutin (CAS No. 497-76-7, EC No. 207-8503) in cosmetic products, preliminary version of 15-16 March 2022, final version of 31 January 2023, SCCS/1642/22

Identified ingredients

  • ALPHA-ARBUTIN

Direct matches are limited for this record, so nearby entries from Annex III are shown as well.

Annex III 378
Shared product type

Arbutin

CAS: 497-76-7
EC: 207-850-3
Annex V 32
Shared product type

CLIMBAZOLE

CAS: 38083-17-9
EC: 253-775-4
Annex III 375
Nearby record in the same annex

Kojic Acid

CAS: 501-30-4
EC: 207-922-4
Annex III 379
Nearby record in the same annex

Silver

CAS: 7440-22-4
EC: 231-131-3
Annex III 374
Nearby record in the same annex

Daidzein

CAS: 486-66-8
EC: 207-635-4

About this record

This page provides a structured view of a cosmetic ingredient record from the EU cosmetic ingredient reference database.

Use the annex link, CAS number, EC number and related records to continue exploring restrictions, warnings, allowed uses and associated reference data.