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Annex II Entry 1265 21/10/2010

2,3-Dihydro-2,2-dimethyl-6-[(4-(phenylazo)-1-naphthelenyl)azo]-1H-pyrimidine (Solvent Black 3) and its salts, when used as a substance in hair dye products

2,3-Dihydro-2,2-dimethyl-6-[(4-(phenylazo)-1-naphthelenyl)azo]-1H-pyrimidine (Solvent Black 3) and its salts, when used as a substance in hair dye products is listed in Annex II as a prohibited substance for cosmetic products placed on the EU market.

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Prohibited substance— Annex II, EU Regulation 1223/2009
Entry: 1265

Chemical identity and properties

PubChem 2D chemical structure for CAS 4197-25-5
CAS 4197-25-5PubChem CID 61336

Sudan Black B

Sudan black B is a member of the class of perimidines that is 2,2-dimethyl-2,3-dihydro-1H-perimidine carrying a [4-(phenyldiazenyl)naphthalen-1-yl]diazenyl substituent at position 6. A fat-soluble dye predominantly used for demonstrating triglycerides in frozen sections and for staining of protein bound lipids in paraffin sections. It has a role as a histological dye. It is a member of azobenzenes, a member of perimidines and a bis(azo) compound. — ChEBI

IUPAC name
(2,2-dimethyl-1,3-dihydroperimidin-6-yl)-(4-phenyldiazenylnaphthalen-1-yl)diazene
Molecular formula
C29H24N6
Molecular weight
456.5 g/mol
Exact mass
456.20624479 Da
XLogP3
8.4
Topological polar surface area
73.5 Ų
Hydrogen-bond donors
2
Hydrogen-bond acceptors
6
Covalent units
1
Defined stereocentres
0

Also known as

Fat Black HBC.I. Solvent Black 3Ceres Black BNFast Black HBTypogen BlackLacquer Black SNubian Black BTHexatype Black B
16 more reported names
Lacquer Black VBFast Black HBNSudan Deep Black BBSudan Deep Black BNC.I. 26150Aizen SOT Black 6Sudan Black X 60Fat Black HB 01Neptune Black X 60CHEBI:88216RefChem:889476Solvent black 3Sudan BlackSOT-Black 6CI 26150NSC 11239
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Record details

Chemical name

2,3-Dihydro-2,2-dimethyl-6-[(4-(phenylazo)-1-naphthelenyl)azo]-1H-pyrimidine (Solvent Black 3) and its salts, when used as a substance in hair dye products

Regulatory information

Regulation

(EC) 2009/1223

See every entry this act set

SCCS opinions

  • Opinion concerning Use of Permanent Hair Dyes and Bladder Cancer - Updated 2004
  • Opinion concerning Hair Dyes without File submitted
  • Opinion on Personal Use of Hair Dyes and Cancer Risk
  • Opinion on the Use of Permanent Hair Dyes and Bladder Cancer Risk
  • Assessment Strategies for Hair Dyes

Identified ingredients

Key data

CAS
4197-25-5
EC
224-087-1
Annex
II
Entry number
1265

Inventory links for 2,3-Dihydro-2,2-dimethyl-6-[(4-(phenylazo)-1-naphthelenyl)azo]-1H-pyrimidine (Solvent Black 3) and its salts, when used as a substance in hair dye products

Inventory Restriction reference
Ref 38148

SOLVENT BLACK 3

CAS: 4197-25-5
EC: 224-087-1

Direct matches are limited for this record, so nearby entries from Annex II are shown as well.

What Annex II means for 2,3-Dihydro-2,2-dimethyl-6-[(4-(phenylazo)-1-naphthelenyl)azo]-1H-pyrimidine (Solvent Black 3) and its salts, when used as a substance in hair dye products

2,3-Dihydro-2,2-dimethyl-6-[(4-(phenylazo)-1-naphthelenyl)azo]-1H-pyrimidine (Solvent Black 3) and its salts, when used as a substance in hair dye products is listed as a prohibited substance under Annex II of EU Cosmetics Regulation 1223/2009 and must not be intentionally added. Article 17 separately addresses unintended small quantities that are technically unavoidable under good manufacturing practice and compatible with the Article 3 safety requirement.

Formulators must screen their ingredients and raw materials to ensure none contain this substance. Suppliers should provide documentation confirming absence when requested.

This record is linked to 1 CosIng inventory ingredient for name and identifier cross-reference. The page also surfaces 12 related annex records with overlapping identifiers, annex logic or naming patterns.

Compliance checklist

  • Verify this substance is absent from all raw materials and finished formulations.
  • Request absence confirmation or CoA from raw material suppliers.
  • Document the screening result in the Product Information File (PIF).

Frequently asked questions

Yes. 2,3-Dihydro-2,2-dimethyl-6-[(4-(phenylazo)-1-naphthelenyl)azo]-1H-pyrimidine (Solvent Black 3) and its salts, when used as a substance in hair dye products is listed in Annex II of EU Cosmetics Regulation 1223/2009 and is prohibited as an intentionally added cosmetic ingredient. Article 17 provides a narrow exception for unintended small quantities that are technically unavoidable under good manufacturing practice, provided the product remains safe under Article 3.

CAS 4197-25-5 is the unique numerical identifier assigned to 2,3-Dihydro-2,2-dimethyl-6-[(4-(phenylazo)-1-naphthelenyl)azo]-1H-pyrimidine (Solvent Black 3) and its salts, when used as a substance in hair dye products by the Chemical Abstracts Service. In cosmetic compliance work, the CAS number is used to cross-reference the substance across regulatory databases, raw material specifications and safety assessment reports. Multiple EU annex entries may share the same CAS number if the same substance appears under different conditions or in different annexes.

Use the INCI Checker tool on this site to paste your full ingredient list (INCI) and scan it against all Annex II–VI entries. The tool highlights any ingredients that match restricted, prohibited or allergen-flagged records. This is useful for rapid compliance screening of finished product formulas or raw material declarations.
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Source note for Annex II record 2,3-Dihydro-2,2-dimethyl-6-[(4-(phenylazo)-1-naphthelenyl)azo]-1H-pyrimidine (Solvent Black 3) and its salts, when used as a substance in hair dye products

This page summarizes one Annex II record for 2,3-Dihydro-2,2-dimethyl-6-[(4-(phenylazo)-1-naphthelenyl)azo]-1H-pyrimidine (Solvent Black 3) and its salts, when used as a substance in hair dye products from public European Commission cosmetic materials and adds linked inventory or identifier matches when available.

Use this record page to review Annex II conditions for 2,3-Dihydro-2,2-dimethyl-6-[(4-(phenylazo)-1-naphthelenyl)azo]-1H-pyrimidine (Solvent Black 3) and its salts, when used as a substance in hair dye products, but confirm any final regulatory decision against the current official annex wording and source files.

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