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Official EU label nameGlossary entry 3215

BENZOPHENONE

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 5 of 13 indexed market datasets: 4 country records and 1 EU Annex records. Every result and evidence gap is listed below.

5 markets with evidence
Markets checked
13
Markets with evidence
5
Evidence gaps
8
Resolved identifiers
3

A missing local match is not permission, approval or proof of safety. It means no strong identity match was resolved in that indexed dataset.

Resolved substance identity

CAS:119-61-919-61-9
EC:204-337-6
Ingredient index records:
BENZOPHENONE
Cosmetic functions: FRAGRANCE, UV ABSORBER

Benzophenone

Open full local profile
2 matched or reported names
BENZOPHENONEBenzophenone

Regulatory evidence in all 13 markets

Open each matched record for its scope, concentration, conditions, warnings and official source version.

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MarketResultRecordsDatasetMeaning / next action
European Union
EU
Prohibited1Open record 1
Complete annex dataset
Regulation (EC) 1223/2009 consolidated to 1 May 2026
Review every linked record and exact conditions.
Great Britain
GB
Prohibited1Open record 1
Complete consolidated annex dataset
GB retained Regulation 1223/2009 schedules, effective 15 August 2026
Review every linked record and exact conditions.
Canada
CA
Restricted1Open record 1
Complete Hotlist snapshot
Health Canada Cosmetic Ingredient Hotlist, 13 August 2025
Review every linked record and exact conditions.
New Zealand
NZ
No local match0
Complete schedules dataset
Cosmetic Products Group Standard schedules effective 1 January 2026
The searchable spreadsheet is an aid; the legal Group Standard and incorporated notices remain authoritative.
ASEAN
ASEAN
Prohibited1Open record 1
Complete regional annex dataset
ASEAN Cosmetic Directive annexes 2026-1, 22 June 2026
Review every linked record and exact conditions.
China
CN
No local match0
Complete prohibited catalogues plus official-source workflow
NMPA 2021 banned catalogues plus dynamic IECIC List I/List II system current since 2025
IECIC listing is not blanket approval; absence may require the new cosmetic ingredient route, and restrictions are checked separately.
Japan
JP
No local match0
Complete Standards appendices dataset
MHLW Standards for Cosmetics official English source and Japanese amendments checked for the imported snapshot
The Japanese text and subsequent notices are canonical; no local match is not a product-compliance conclusion.
South Korea
KR
No local match0
Complete current appendix dataset
MFDS Notice 2026-19, effective 18 March 2026
Korean source wording is canonical and other positive lists/notices may still apply to the formulation.
United States
US
No local match0
Complete enumerated federal ingredient rules
eCFR Title 21 issue date 27 August 2026
FDA has no general approved-cosmetic-ingredient catalogue; absence from these sections is not approval or proof of safety.
Australia
AU
No local match0
Complete cosmetic-relevant Poisons Standard subset plus official workflow
Therapeutic Goods (Poisons Standard—June 2026) Instrument 2026
An AICIS Inventory match is not cosmetic approval; no Inventory match can indicate a new, exempted, reported or confidential introduction.
Brazil
BR
No local match0
Complete prohibited dataset plus current restricted-list workflow
ANVISA RDC 1.029/2026 and RDC 1.030/2026, published 15 June 2026
RDC 1.030/2026 amends rather than replaces the prohibited baseline, and the second restricted-list revision was still under consultation in July 2026.
India
IN
No local match0
Complete current Part 2 dataset plus official workflow for Parts 1, 3 and 4
Cosmetics Rules 2020 plus current BIS IS 4707 parts (1:2020, 2:2025, 3:2025, 4:2022)
The standards are separate controlled publications; absence from a locally indexed excerpt is not permission.
Saudi Arabia
SA
Prohibited1Open record 1
Complete official list index
SFDA live prohibited/restricted lists, snapshot 30 August 2026
Review every linked record and exact conditions.
No market rows match this filter.

Matching market records and conditions

Exact Annex II–VI evidence

Chemical identity and properties

PubChem 2D chemical structure for CAS 119-61-9
CAS 119-61-9PubChem CID 3102

Benzophenone

IUPAC name
diphenylmethanone
Molecular formula
C13H10O
Molecular weight
182.22 g/mol
Exact mass
182.073164938 Da
XLogP3
3.4
Topological polar surface area
17.1 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
1
Covalent units
1
Defined stereocentres
0

Also known as

Diphenyl ketoneBenzoylbenzeneMethanone, diphenyl-Phenyl ketonealpha-OxoditaneKetone, diphenylDiphenylketoneBenzene, benzoyl-
16 more reported names
alpha-OxodiphenylmethaneKayacure bpAdjutan 6016Caswell No. 081GFEMA No. 2134NSC 8077CCRIS 629EPA Pesticide Chemical Code 000315701M4TTV9OCHEBI:41308AI3-00754NSC-8077RefChem:916948204-337-6diphenyl-methanone.alpha.-Oxoditane
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match3102

Attributed physical-property, hazard, environmental and use annotations.

  • First Aid: EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.; SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.; INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) shou Source: CAMEO Chemicals
  • Signal: Danger Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • GHS Hazard Statements: H350: May cause cancer [Danger Carcinogenicity] Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • Precautionary Statement Codes: P203, P280, P318, P405, and P501 (click each P-code to see the statement) Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • Note: This chemical does not meet GHS hazard criteria for 1.8% (84 of 4790) of reports. Source: European Chemicals Agency (ECHA)
  • Signal: Warning Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H373 (37.4%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]; H411 (74.8%): Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P260, P273, P319, P391, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 4790 reports by companies from 68 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 84 of 4790 reports by companies.; There are 67 notifications provided by 4706 of 4790 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Signal: Danger Source: NITE-CMC
  • GHS Hazard Statements: H302: Harmful if swallowed [Warning Acute toxicity, oral]; H350: May cause cancer [Danger Carcinogenicity]; H373: May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure] Source: NITE-CMC
  • Precautionary Statement Codes: P203, P260, P264, P270, P280, P301+P317, P318, P319, P330, P405, and P501 (click each P-code to see the statement) Source: NITE-CMC
  • Signal: Warning Source: NITE-CMC
  • Health Effects: Acute exposure to cholinesterase inhibitors can cause a cholinergic crisis characterized by severe nausea/vomiting, salivation, sweating, bradycardia, hypotension, collapse, and convulsions. Increasing muscle weakness is a possibility and may result in death if respiratory muscles are involved. Accumulation of ACh at motor nerves causes overstimulation of nicotinic expression at the neuromuscular junction. When this occurs symptoms such as muscle weakness, fatigue, muscle cramps, fasciculation, and paralysis can be seen. When there is an accumulation of ACh at autonomic ganglia this causes overstimulation of nicotinic expression in the sympathetic system. Symptoms associated with this are hypertension, and hypoglycemia. Overstimulation of nicotinic acetylcholine receptors in the central nervous system, due to accumulation of ACh, results in anxiety, headache, convulsions, ataxia, depression of respiration and circulation, tremor, general weakness, and potentially coma. When there is expression of muscarinic overstimulation due to excess acetylcholine at muscarinic acetylcholine receptors symptoms of visual disturbances, tightness in chest, wheezing due to bronchoconstriction, incre Source: Toxin and Toxin Target Database (T3DB)
  • Toxicity Summary: IDENTIFICATION AND USE: Benzophenone (BZP) comes in the form of orthorhombic prisms, monoclinic prisms, and white crystals. It has a characteristic sweet geranium or rose-like odor. BZP is used as a photoinitiator, a fragrance enhancer, an ultraviolet stabilizer, and, occasionally, as a flavor ingredient; it is also used in the manufacture of insecticides, agricultural chemicals, pharmaceuticals (antihistamines), hypnotics, paints, lacquers and cosmetics; and is an additive for plastics, coatings, and adhesives. Not registered for current use as a pesticide in the U.S., but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses. HUMAN EXPOSURE AND TOXICITY: There is limited information on the toxic effects of BZP in humans published. It showed little activity in the hormone-responsive reporter assay tested in various cell lines. ANIMAL STUDIES: BZP showed no estrogenic activity, however, after irradiating an aqueous solution of BZP with UV or sunlight, it can be converted into ring-hydroxylated derivatives (3-hydroxy BP (BP-3OH) and 4-hydroxyBP (BP-4OH)) that have estrogenic activity. BP-4OH was more Source: Hazardous Substances Data Bank (HSDB)
  • Toxicity Summary: Benzophenone is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinesterase. Because of its essential function, chemicals that interfere with the action of acetylcholinesterase are potent neurotoxins, causing excessive salivation and eye-watering in low doses, followed by muscle spasms and ultimately death. Nerve gases and many substances used in insecticides have been shown to act by binding a serine in the active site of acetylcholine esterase, inhibiting the enzyme completely. Acetylcholine esterase breaks down the neurotransmitter acetylcholine, which is released at nerve and muscle junctions, in order to allow the muscle or organ to relax. The result of acetylcholine esterase inhibition is that acetylcholine builds up and continues to act so that any nerve impulses are continually transmitted and muscle contractions do not stop. Among the most common acetylcholinesterase inhibitors are phosphorus-based compounds, which are designed to bind to the active site of the enzyme. The structural requirements are a phosphorus atom bearing two lipophilic groups, a leaving group (such as a h Source: Toxin and Toxin Target Database (T3DB)
  • Environmental Bioconcentration: BCF values of 3.4-9.2 were measured using carp (Cyprinus carpio) which were exposed to benzophenone concentrations of 0.3 ppm over an 6-week period(1). According to a classification scheme(2), this BCF range suggests the potential for bioconcentration in aquatic organisms is low(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: TERRESTRIAL FATE: Based on a classification scheme(1), Koc values of 413(2) and 517(3) indicate that benzophenone is expected to have moderate to low mobility in soil(SRC). Volatilization of benzophenone from moist soil surfaces is expected to be an important fate process(SRC) given an estimated Henry's Law constant of 1.9X10-6 atm-cu m/mole(SRC), based upon its vapor pressure, 1.93X10-3 mm Hg(4), and water solubility, 137 mg/L(5). Benzophenone is not expected to volatilize from dry soil surfaces(SRC) based upon its vapor pressure(4). Utilizing the Japanese MITI test, 0% of the Theoretical BOD was reached in 2 weeks(6) indicating that biodegradation is not an important environmental fate process in soil(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: AQUATIC FATE: Based on a classification scheme(1), Koc values of 430(2) and 517(3) indicate that benzophenone is not expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is expected(4) based upon an estimated Henry's Law constant of 1.9X10-6 atm-cu m/mole(SRC), derived from its vapor pressure, 1.93X10-3 mm Hg(5), and water solubility, 137 mg/L(6). Using this Henry's Law constant and an estimation method(4), volatilization half-lives for a model river and model lake are 15 and 110 days, respectively(SRC). According to a classification scheme(7), a BCF range of 3.4-9.2(8) suggests that bioconcentration in aquatic organisms is low(SRC). Utilizing the Japanese MITI test, 0% of the Theoretical BOD was reached in 2 weeks(8) indicating that biodegradation is not an important environmental fate process in water(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), benzophenone, which has a vapor pressure of 1.93X10-3 mm Hg at 25 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase benzophenone is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 3 days(SRC), calculated from its rate constant of 3.6X10-12 cu cm/molecule-sec at 25 °C(SRC) that was derived using a structure estimation method(3). Benzophenone absorbs UV light at wavelengths >290 nm(4) and, therefore, may be susceptible to direct photolysis by sunlight(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Industry Uses: Photosensitive agent; Surface modifier; Not Known or Reasonably Ascertainable; Anti-stain agent; Tanning agents not otherwise specified Source: EPA Chemical Data Reporting (CDR)
  • Sources/Uses: Used in perfumes, flavoring agents, and organic synthesis; Also used as an inhibitor of styrene polymerization, a photoinitiator, an ultraviolet curing agent, and an additive (plastics, cosmetics, coatings, and adhesives); [HSDB] Occurs naturally in some foods; [AIHA] Benzophenone (BZP), and substituted BZP numbered 1-12, trade mark Uvinul, are photo-screen agents widely used in sunscreens and in cosmetics, such as antiaging creams and hair sprays and shampoos, paints, and plastics. [Kanerva, p. 1755] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
  • Industrial Processes with risk of exposure: Painting (Pigments, Binders, and Biocides) [Category: Paint]; Working with Glues and Adhesives [Category: Other]; Plastic Composites Manufacturing [Category: Industry] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
  • Uses: For benzophenone (USEPA/OPP Pesticide Code: 000315) there are 0 labels match. /SRP: Not registered for current use in the U.S., but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses./ Source: Hazardous Substances Data Bank (HSDB)
  • Uses: Fixative for heavy perfumes, such as geranium, new-mown hay, especially when used in soaps. In the manufacture of antihistamines, hypnotics, insecticides. Source: Hazardous Substances Data Bank (HSDB)
  • Uses: Organic synthesis; ... derivatives are used as ultraviolet absorbers; flavoring; ... polymerization inhibitor for styrene Source: Hazardous Substances Data Bank (HSDB)
  • Uses: Paints, lacquers and varnish industry, cosmetics, intermediate. Source: Hazardous Substances Data Bank (HSDB)
  • Uses: For more Uses (Complete) data for BENZOPHENONE (7 total), please visit the HSDB record page. Source: Hazardous Substances Data Bank (HSDB)
  • Uses: Benzophenone is found in fruits. Benzophenone is a widely used building block in organic chemistry, being the parent diarylketone. Source: Toxin and Toxin Target Database (T3DB)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

These source-specific lookups can add hazard, toxicology, identity and assessment context. A link is a research route, not a claim that the source contains an exact record.

Cosmetic Ingredient Review safety assessments

Expert Panel conclusions, assessed ingredient groups, use conditions, dates and report documents

Independent expert review considered by FDA; not a government approval or binding market rule

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FDA Global Substance Registration System

UNII identifiers, preferred names, substance types, codes and public substance relationships

Identity registry only; UNII availability does not imply FDA review or approval

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ILO/WHO International Chemical Safety Cards

Hazards, symptoms, first aid, storage, incompatibilities and physical properties for covered chemicals

International occupational chemical-safety reference; not cosmetic-use approval

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Japan NITE-CHRIP

Chemical identity, Japanese and foreign legal lists, GHS hazards and exposure-related information

Chemical-management evidence; cosmetic status remains governed by the applicable MHLW standard and market rules

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NIOSH Pocket Guide to Chemical Hazards

REL, PEL, IDLH, properties, exposure routes, symptoms, target organs, first aid and measurement methods for covered workplace chemicals

US occupational-health guidance and limits; not a cosmetic ingredient decision

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OECD eChemPortal

Gateway to authority-owned physical-property, fate, ecotoxicity, toxicity, exposure and GHS records

Discovery gateway; each linked authority remains responsible for its data

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US EPA CompTox CTX APIs

DTXSID identity, experimental and predicted properties, toxicity, bioactivity, exposure and environmental data

Scientific and computational evidence; predictions must remain labelled and do not determine cosmetic legality

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Continue the compliance check

1. Confirm identity

Match the supplier specification, CAS/EC identifiers and composition to this official label name. Similar wording is not proof of chemical equivalence.

2. Review restrictions

Check every exact Annex record shown above, plus CMR, nanomaterial, SCCS and later-amendment requirements that may apply.

3. Verify the formula

Evaluate concentration, product type, purity, warnings, claims and each target market before making a compliance decision.

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

Open official Decision