Official EU label nameGlossary entry 18381

ORIDONIN

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

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Resolved identifiers

Resolved substance identity

CAS:28957-04-2

Ingredient index records:

ORIDONIN

Cosmetic functions: SKIN CONDITIONING

(1alpha, 6beta,7alpha,14R)-7,20-Epoxy-1,6,7,14-tetrahydroxykaur-16-en-15-one

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1 matched or reported name

ORIDONIN

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name ORIDONIN.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 28957-04-2

CAS 28957-04-2PubChem CID 5321010

Oridonin

Oridonin is an organic heteropentacyclic compound and ent-kaurane diterpenoid with formula C20H28O6 isolated from the leaves of the medicinal herb Rabdosia rubescens. It has a role as an antibacterial agent, an antineoplastic agent, an angiogenesis inhibitor, an anti-asthmatic agent, an apoptosis inducer and a plant metabolite. It is a secondary alcohol, an ent-kaurane diterpenoid, an organic heteropentacyclic compound, an enone and a cyclic hemiketal. — ChEBI

IUPAC name: (1S,2S,5S,8R,9S,10S,11R,15S,18R)-9,10,15,18-tetrahydroxy-12,12-dimethyl-6-methylidene-17-oxapentacyclo[7.6.2.15,8.01,11.02,8]octadecan-7-one

Molecular formula: C20H28O6
Molecular weight: 364.4 g/mol
Exact mass: 364.18858861 Da
XLogP3: 0.1
Topological polar surface area: 107.0 Å²
Hydrogen-bond donors: 4
Hydrogen-bond acceptors: 6
Covalent units: 1
Defined stereocentres: 9

Also known as

OridonineISODONOLlasidoninPURE ORIDONIN0APJ98UCLQNSC-250682CHEBI:138236Kaur-16-en-15-one, 7,20-epoxy-1,6,7,14-tetrahydroxy-, (1alpha,6beta,7alpha,14R)-

16 more reported names

(1S,2S,5S,8R,9S,10S,11R,15S,18R)-9,10,15,18-tetrahydroxy-12,12-dimethyl-6-methylidene-17-oxapentacyclo(7.6.2.15,8.01,11.02,8)octadecan-7-oneRefChem:168506(1S,2S,5S,8R,9R,10S,11R,15S,18R)-9,10,15,18-tetrahydroxy-12,12-dimethyl-6-methylidene-17-oxapentacyclo(7.6.2.15,8.01,11.02,8)octadecan-7-one631-100-89,10,15,18-tetrahydroxy-12,12-dimethyl-6-methylidene-17-oxapentacyclo(7.6.2.15,8.01,11.02,8)octadecan-7-oneRubescensin AUNII-0APJ98UCLQNSC 250682NSC-250682; IsodonolRubescensin;20-Epoxy-1-alpha,6-beta,7,14-tetrahydroxy-7-alph(14r)-kaur-16-en-15-on(14R)-7-alpha,20-Epoxy-1-alpha,6-beta,7,14-tetrahydroxykaur-16-en-15-oneOridonin (Standard)CS-0007086Curator_0000067a,20-Epoxy-1a,6b,7,14-tetrahydroxy-Kaur-16-en-15-one

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External database identifiers

ChEBI:CHEBI:138236
ChEMBL:CHEMBL1164920
EPA DTXSID:DTXSID201021760
PubMed:38972361
PubMed:37993134
PubMed:37871880
PubMed:37486694
PubMed:37155118
PubMed:36894905
PubMed:36573068
PubMed:35686337
PubMed:35405616
PubMed:35039992
PubMed:31594861
PubMed:31430510

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

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Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal US EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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