Methyl Laurate
- IUPAC name
- methyl dodecanoate
- Molecular formula
- C13H26O2
- Molecular weight
- 214.34 g/mol
- Exact mass
- 214.193280068 Da
- XLogP3
- 5.8
- Topological polar surface area
- 26.3 Ų
- Hydrogen-bond donors
- 0
- Hydrogen-bond acceptors
- 2
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
16 more reported names
External database identifiers
- ChEBI:CHEBI:87494
- ChEMBL:CHEMBL1894365
- EPA DTXSID:DTXSID5026889
- PubMed:27633901
- PubMed:22975784
- PubMed:22885112
- PubMed:22649385
- PubMed:22238638
- PubMed:22163873
- PubMed:21057946
- PubMed:20129777
- PubMed:20104349
- PubMed:19876644
- PubMed:19572886
- PubMed:18788736
Evidence from additional scientific databases
NIH PubChem PUG-View
Attributed physical-property, hazard, environmental and use annotations.
- Boiling Point: 267 °C Source: Hazardous Substances Data Bank (HSDB)
- Boiling Point: 148.00 °C. @ 18.00 mm Hg Source: Human Metabolome Database (HMDB)
- Boiling Point: 261-262 °C Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Color/Form: COLORLESS LIQUID Source: Hazardous Substances Data Bank (HSDB)
- Color/Form: Water-white liquid Source: Hazardous Substances Data Bank (HSDB)
- Density: 0.8702 @ 20 °C/4 °C Source: Hazardous Substances Data Bank (HSDB)
- Density: 0.863-0.872 Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- LogP: log Kow= 5.41 Source: Hazardous Substances Data Bank (HSDB)
- LogP: 5.41 Source: Human Metabolome Database (HMDB)
- Melting Point: 5.2 °C Source: Hazardous Substances Data Bank (HSDB)
- Melting Point: 5 °C Source: Human Metabolome Database (HMDB)
- Odor: FATTY, FLORAL ODOR REMINISCENT OF WINE Source: Hazardous Substances Data Bank (HSDB)
- Odor: OILY, WINEY, FATTY ODOR Source: Hazardous Substances Data Bank (HSDB)
- Physical Description: Liquid; Dry Powder; Liquid; CBI Source: EPA Chemical Data Reporting (CDR)
- Physical Description: Water-white liquid; mp = 4.8 deg C; [Hawley] Colorless liquid; [MSDSonline] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Physical Description: Liquid Source: Human Metabolome Database (HMDB)
- Physical Description: colourless to pale yellow liquid with a fatty, floral, winey odour Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Refractive Index: Index of refraction: 1.4301 @ 25 °C/D Source: Hazardous Substances Data Bank (HSDB)
- Refractive Index: index of refraction: 1.4319 @ 20 °C/D Source: Hazardous Substances Data Bank (HSDB)
- Refractive Index: 1.430-1.438 Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Solubility: Insol in water; miscible with ethyl alcohol, ether, acetone Source: Hazardous Substances Data Bank (HSDB)
- Solubility: SOL IN MOST COMMON ORGANIC SOLVENTS Source: Hazardous Substances Data Bank (HSDB)
- Solubility: soluble in most organic solvents; insoluble in water Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Solubility: (in ethanol) Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Vapor Pressure: 0.00411 [mmHg] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Vapor Pressure: 4.11X10-3 mm Hg @ 25 °C Source: Hazardous Substances Data Bank (HSDB)
- Carcinogen Classification: No indication of carcinogenicity to humans (not listed by IARC). Source: Toxin and Toxin Target Database (T3DB)
- Note: This chemical does not meet GHS hazard criteria for 12.2% (52 of 426) of reports. Source: European Chemicals Agency (ECHA)
- Signal: Warning Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H400 (74.6%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]; H411 (65.5%): Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard] Source: European Chemicals Agency (ECHA)
- Precautionary Statement Codes: P273, P391, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 426 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 52 of 426 reports by companies.; There are 9 notifications provided by 374 of 426 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- Signal: Warning Source: NITE-CMC
- GHS Hazard Statements: H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]; H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Source: NITE-CMC
- Precautionary Statement Codes: P273, P391, and P501 (click each P-code to see the statement) Source: NITE-CMC
- GHS Hazard Statements: H336: May cause drowsiness or dizziness [Warning Specific target organ toxicity, single exposure; Narcotic effects]; H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]; H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Source: NITE-CMC
- Precautionary Statement Codes: P261, P271, P273, P304+P340, P319, P391, P403+P233, P405, and P501 (click each P-code to see the statement) Source: NITE-CMC
- GHS Hazard Statements: H315: Causes skin irritation [Warning Skin corrosion/irritation]; H320: Causes eye irritation [Warning Serious eye damage/eye irritation]; H336: May cause drowsiness or dizziness [Warning Specific target organ toxicity, single exposure; Narcotic effects]; H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]; H411: Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard] Source: NITE-CMC
- Precautionary Statement Codes: P261, P264, P264+P265, P271, P273, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement) Source: NITE-CMC
- Environmental Bioconcentration: An estimated BCF of 290 was calculated for methyl dodecanoate(SRC) using a log Kow of 5.41(1) and a regression-derived equation(2). According to a classification scheme(3), the estimated BCF suggests the potential for bioconcentration in aquatic organisms is high. However, bioconcentration studies on compounds which are structurally similar(4,5) suggests that bioconcentration may be lower than that indicated by the regression-derived equation due to the ability of aquatic organisms to readily metabolize this class of compounds(SRC). Source: Hazardous Substances Data Bank (HSDB)
- Environmental Fate: TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 1,600(SRC), determined from a structure estimation method(2), indicates that methyl dodecanoate is expected to be immobile in soil(SRC). Volatilization of methyl dodecanoate from moist soil surfaces is expected to be an important fate process(SRC) given an estimated Henry's Law constant of 0.003 atm-cu m/mole(SRC), using a fragment constant estimation method(3). However, adsorption to soil is expected to attenuate volatilization(SRC). Methyl dodecanoate is not expected to volatilize from dry soil surfaces(SRC) based upon a vapor pressure of 0.004 mm Hg(4). Methyl dodecanoate is expected to rapidly biodegrade in aerobic soils by analogy to structurally similar long-chain fatty acid esters(5-7). Source: Hazardous Substances Data Bank (HSDB)
- Environmental Fate: AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 1,600(SRC), determined from a structure estimation method(2), indicates that methyl dodecanoate is expected to adsorb to suspended solids and sediment in water(SRC). Volatilization from water surfaces is expected(3) based upon an estimated Henry's Law constant of 0.003 atm-cu m/mole(SRC), developed using a fragment constant estimation method(4). Volatilization half-lives for a model river and model lake are 5 hours and 6 days, respectively(SRC), using an estimation method(3). However, volatilization from water surfaces is expected to be attenuated by adsorption to suspended solids and sediment in the water column(SRC). The volatilization half-life from a model pond is estimated to be about 56 hours ignoring adsorption; when considering maximum adsorption the volatilization half-life increases to 14 days(5). According to a classification scheme(6), an estimated BCF of 290(SRC) from its log Kow of 5.41(12) and a regression-derived equation(7), suggests the potential for bioconcentration in aquatic organisms is high although it may be lower than that indicated due to the expected rapid metabolism rate for thi Source: Hazardous Substances Data Bank (HSDB)
- Environmental Fate: ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), methyl dodecanoate, which has a vapor pressure of 0.0041 mm Hg at 25 °C(2), will exist in solely as a vapor in the ambient atmosphere. Vapor-phase methyl dodecanoate is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 29 hours(SRC) from its estimated rate constant of 1.3X10-11 cu cm/molecule-sec at 25 °C(3). Source: Hazardous Substances Data Bank (HSDB)
- Consumer Uses: Binder; Softener and conditioner; Not Known or Reasonably Ascertainable; Emulsifier Source: EPA Chemical Data Reporting (CDR)
- Industry Uses: Lubricating agent; Binder; Other; Solvent; Softener and conditioner; Intermediate; Emulsifier; Not Known or Reasonably Ascertainable Source: EPA Chemical Data Reporting (CDR)
- Sources/Uses: Made from coconut oil; [Hawley] Used as a flavoring agent and as an intermediate for detergents, emulsifiers, wetting agents, stabilizers, lubricants, plasticizers, textiles, alkanolamides, fatty alcohols, and acids; [HSDB] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Uses: Intermediate for detergents, emulsifiers, wetting agents, stabilizers, lubricants, plasticizers, textiles, flavoring Source: Hazardous Substances Data Bank (HSDB)
- Uses: CHEM INT-EG, FOR ALKANOLAMIDES, FATTY ALCOHOLS & ACIDS Source: Hazardous Substances Data Bank (HSDB)
- Uses: FLAVORING AGENT, EG, IN BAKED GOODS & ICE CREAM Source: Hazardous Substances Data Bank (HSDB)
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.