Skip to content
Annex III Entry 225 05/06/2014

1-(beta-Hydroxyethyl)amino-2-nitro-4-N-ethyl-N-(beta-hydroxyethyl)aminobenzene and its hydrocloride

HC BLUE NO. 12

Key data

Source and verification note

CosIng Checker is an independent reference website built from publicly available European Commission cosmetic ingredient materials, including Annex II–VI datasets.

Use these pages for research, discovery and comparison, but verify critical regulatory decisions against the official source text and current law.

Record details

INCI glossary name

HC BLUE NO. 12

Chemical name

1-(beta-Hydroxyethyl)amino-2-nitro-4-N-ethyl-N-(beta-hydroxyethyl)aminobenzene and its hydrocloride

Chemical / IUPAC name

1-(beta-Hydroxyethyl)amino-2-nitro-4- N-ethyl-N-(.beta.- hydroxyethyl)aminobenzene and its hydrochloride

Maximum concentration

(b) 1.5% (as hydrocloride)

Other restrictions

(a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0.75% (as hydrochloride)
For (a) and (b):
- Do not use with nitrosating agents
-Maximum nitrosamine content: 50 microgram/Kg
- Keep in nitrite-free containers

Warnings

(a) To be printed on the label: The mixing ratio. “ Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary ‘black henna’ tattoo in the past.

Regulatory information

Regulation

(EC) 2013/344

SCCS opinions

  • Request for a Re-evaluation of hair dyes listed in Annex III to Directive 76/768/EEC on Cosmetic Products
  • Opinion concerning Use of Permanent Hair Dyes and Bladder Cancer - Updated 2004
  • Opinion on Personal Use of Hair Dyes and Cancer Risk
  • Opinion on the Use of Permanent Hair Dyes and Bladder Cancer Risk
  • Assessment Strategies for Hair Dyes
  • Opinion on HC Blue No. 12
  • Memorandum on Hair Dye Substances and their Skin Sensitising Properties
  • Opinion on HC Blue No. 12
  • Opinion on HC Blue No. 12

Identified ingredients

  • HC BLUE NO. 12
Annex III 16
Shared product type

1-NAPHTHOL

CAS: 90-15-3
EC: 201-969-4
Annex III 16
Shared product type

1-Naphthol

CAS: 90-15-3
EC: 201-969-4
Annex III 190
Shared product type

ACID BLUE 9

CAS: 3844-45-9 - 2650-18-2 - 68921-42-6
EC: 223-339-8 - 220-168-0 - 272-939-6
Annex III 191
Shared product type

CURRY RED

CAS: 25956-17-6
EC: 247-368-0
Annex III 192
Shared product type

ACID RED 18

CAS: 2611-82-7 - 12227-64-4
EC: 220-036-2 - 235-438-3
Annex III 193
Shared product type

ACID RED 52

CAS: 3520-42-1
EC: 222-529-8
Annex III 195
Shared product type

ACID BLUE 62

CAS: 4368-56-3
EC: 224-460-9
Annex III 196
Shared product type

HC BLUE NO. 11

CAS: 23920-15-2
EC: 459-980-7

About this record

This page provides a structured view of a cosmetic ingredient record from the EU cosmetic ingredient reference database.

Use the annex link, CAS number, EC number and related records to continue exploring restrictions, warnings, allowed uses and associated reference data.